Evidence for scale up: the differentiated care research agenda

Evidence for scale up: the differentiated care research agenda

The scale up of antiretroviral therapy (ART) to more than 18 million people living with HIV (PLHIV) [1], primarily in lowand middle-income countries, is one of history’s greatest public health achievements. Life expectancy among PLHIV on ART has improved worldwide [2], and in some settings hardest hit by the epidemic, rapid gains have been seen. For example, in KwaZulu-Natal, South Africa, life...

The research agenda for protocol-based care.

Background Protocol-based care is increasingly being used to deliver collaborative, integrated and improved patient-centred care, based on the best available evidence. This article provides an overview of key issues arising from protocol-based care literature to illustrate the research agenda for this important care delivery approach. Conclusion Protocols provide great potential to deliver best...

The impact of HIV scale-up on health systems: A priority research agenda.

Although much has been learned about the implementation of HIV prevention, care, and treatment services in resource-limited settings, the broader impact of the rapid scale-up of HIV programs on fragile health systems has only recently been explored. A high-level working group identified priority research questions regarding the impact of HIV scale-up on key elements of health systems: service d...

Research-agenda Bias: letters to the editor

The Many Meanings of Evidence: Implications for the Translational Science Agenda in Healthcare

Health systems across the world are concerned with the quality and safety of patient care. This includes investing in research and development to progress advances in the treatment and management of individuals and healthcare organisations. The concept of evidence- based healthcare has gained increasing currency over the last two decades; yet questions persist about the time it takes for new re...